Recent research has found that metformin use lowers the risk of gout by 32% in individuals with prediabetes.
Individuals with prediabetes are not only at an elevated risk for diabetes but also face an increased risk of developing gout. This study assessed the gout-lowering properties of metformin in 25,064 individuals with prediabetes. Patients who were initiated on metformin within 18 months after the diagnosis of prediabetes were compared with those who did not use metformin or other antidiabetic medications.
Those patients using metformin were found to have 2.4 fewer cases of gout per 1000 person-years and a 32% reduced relative risk for incident gout. Metformin use was also associated with a reduction in A1c levels and body mass index.
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