A recent research review has concluded that Type 1 diabetes has a significant negative effect on the growth of children.
The review found evidence of debilitated growth in children with Type 1 diabetes and a few anomalies in the growth hormone (GH)-insulin-like growth factor-1 (IGF-1) axis when compared to fit children.
It reported some studies showing that children with Type 1 diabetes were taller before the onset of the disease and during early diagnosis.
The review concluded that the most accepted and effective treatment of impaired growth is the administration of long-acting insulin or continuous rapid-acting insulin. However, it found that height was affected by the administration of good basal insulin at puberty but was unaffected by the continuous subcutaneous insulin injection.
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